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» Some statistical properties of regulatory DNA sequences, and...
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BMCBI
2006
128views more  BMCBI 2006»
13 years 8 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
CEC
2003
IEEE
14 years 1 months ago
Stochastic neural network models for gene regulatory networks
AbstractRecent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of geno...
Tianhai Tian, Kevin Burrage
BMCBI
2007
89views more  BMCBI 2007»
13 years 8 months ago
Comparing segmentations by applying randomization techniques
Background: There exist many segmentation techniques for genomic sequences, and the segmentations can also be based on many different biological features. We show how to evaluate ...
Niina Haiminen, Heikki Mannila, Evimaria Terzi
JCB
2008
170views more  JCB 2008»
13 years 8 months ago
Efficiently Identifying Max-Gap Clusters in Pairwise Genome Comparison
The spatial clustering of genes across different genomes has been used to study important problems in comparative genomics, from identification of operons to detection of homologo...
Xu Ling, Xin He, Dong Xin, Jiawei Han
ALMOB
2006
155views more  ALMOB 2006»
13 years 8 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg