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» Spatio-Temporal Alignment of Sequences
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ALMOB
2006
138views more  ALMOB 2006»
13 years 7 months ago
An enhanced RNA alignment benchmark for sequence alignment programs
Background: The performance of alignment programs is traditionally tested on sets of protein sequences, of which a reference alignment is known. Conclusions drawn from such protei...
Andreas Wilm, Indra Mainz, Gerhard Steger
BMCBI
2007
135views more  BMCBI 2007»
13 years 7 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer
GECCO
2003
Springer
129views Optimization» more  GECCO 2003»
14 years 26 days ago
Evolutionary Two-Dimensional DNA Sequence Alignment
This article presents a model for DNA sequence alignment. In our model, a finite state automaton writes two-dimensional maps of nucleotide sequences. An evolutionary method for se...
Edgar E. Vallejo, Fernando Ramos
RECOMB
2012
Springer
11 years 10 months ago
Estimating the Accuracy of Multiple Alignments and its Use in Parameter Advising
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
Dan F. DeBlasio, Travis J. Wheeler, John D. Kececi...
JCB
2000
91views more  JCB 2000»
13 years 7 months ago
Scaling Laws and Similarity Detection in Sequence Alignment with Gaps
We study the problem of similarity detection by sequence alignment with gaps, using a recently established theoretical framework based on the morphology of alignment paths. Alignm...
Dirk Drasdo, Terence Hwa, Michael Lässig