1112 search results - page 178 / 223 » Spatio-Temporal Alignment of Sequences |
BMCBI
2006
13 years 9 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
BMCBI
2006
13 years 9 months ago
2006
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
BMCBI
2007
13 years 9 months ago
2007
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
BMCBI
2005
13 years 9 months ago
2005
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
BMCBI
2011
13 years 4 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...