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» Spatio-Temporal Alignment of Sequences
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BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Estimating true evolutionary distances under rearrangements, duplications, and losses
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
Yu Lin, Vaibhav Rajan, Krister M. Swenson, Bernard...
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
The LabelHash Algorithm for Substructure Matching
Background: There is an increasing number of proteins with known structure but unknown function. Determining their function would have a significant impact on understanding diseas...
Mark Moll, Drew H. Bryant, Lydia E. Kavraki
BMCBI
2008
80views more  BMCBI 2008»
13 years 7 months ago
Computational evaluation of TIS annotation for prokaryotic genomes
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
Gang-Qing Hu, Xiaobin Zheng, Li-Ning Ju, Huaiqiu Z...