28 search results - page 5 / 6 » Species-specific protein sequence and fold optimizations |
BMCBI
2004
13 years 7 months ago
2004
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
ISMB
1996
13 years 8 months ago
1996
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
RECOMB
2006
Springer
14 years 7 months ago
2006
Springer
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
BMCBI
2006
13 years 7 months ago
2006
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
BMCBI
2008
13 years 7 months ago
2008
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...