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BMCBI
2010
138views more  BMCBI 2010»
13 years 10 months ago
Sigma-2: Multiple sequence alignment of non-coding DNA via an evolutionary model
Background: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a ...
Gayathri Jayaraman, Rahul Siddharthan
BMCBI
2007
104views more  BMCBI 2007»
13 years 10 months ago
Joint mapping of genes and conditions via multidimensional unfolding analysis
Background: Microarray compendia profile the expression of genes in a number of experimental conditions. Such data compendia are useful not only to group genes and conditions base...
Katrijn Van Deun, Kathleen Marchal, Willem J. Heis...
BMCBI
2010
224views more  BMCBI 2010»
13 years 10 months ago
An adaptive optimal ensemble classifier via bagging and rank aggregation with applications to high dimensional data
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
Susmita Datta, Vasyl Pihur, Somnath Datta
BMCBI
2010
87views more  BMCBI 2010»
13 years 10 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2008
125views more  BMCBI 2008»
13 years 10 months ago
Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors
Background: The Potato type II (Pot II) family of proteinase inhibitors plays critical roles in the defense system of plants from Solanaceae family against pests. To better unders...
Lesheng Kong, Shoba Ranganathan