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RECOMB
2008
Springer
14 years 11 months ago
Spectrum Fusion: Using Multiple Mass Spectra for De Novo Peptide Sequencing
We report on a new algorithm for combining the information from several mass spectra of the same peptide. The algorithm automatically learns peptide fragmentation patterns, so that...
Ritendra Datta, Marshall W. Bern
BMCBI
2010
152views more  BMCBI 2010»
13 years 11 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
BMCBI
2010
117views more  BMCBI 2010»
13 years 11 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
IMSCCS
2006
IEEE
14 years 5 months ago
Quality Assessment of Peptide Tandem Mass Spectra
Background: Tandem mass spectrometry has emerged as a cornerstone of high throughput proteomic studies owing in part to various high throughput search engines which are used to in...
Fang-Xiang Wu, Pierre Gagné, Arnaud Droit, ...
CSB
2004
IEEE
110views Bioinformatics» more  CSB 2004»
14 years 2 months ago
SPIDER: Software for Protein Identification from Sequence Tags with De Novo Sequencing Error
For the identification of novel proteins using MS/MS, de novo sequencing software computes one or several possible amino acid sequences (called sequence tags) for each MS/MS spect...
Yonghua Han, Bin Ma, Kaizhong Zhang