Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
In many domains, we are interested in analyzing the structure of the underlying distribution, e.g., whether one variable is a direct parent of the other. Bayesian model selection a...
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
Background: Inference of population stratification and individual admixture from genetic markers is an integrative part of a study in diverse situations, such as association mappi...