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» Spotting effect in microarray experiments
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BMCBI
2006
122views more  BMCBI 2006»
13 years 7 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2008
113views more  BMCBI 2008»
13 years 7 months ago
A novel application of quantile regression for identification of biomarkers exemplified by equine cartilage microarray data
Background: Identification of biomarkers among thousands of genes arrayed for disease classification has been the subject of considerable research in recent years. These studies h...
Liping Huang, Wenying Zhu, Christopher P. Saunders...
BMCBI
2010
91views more  BMCBI 2010»
13 years 6 months ago
Washing scaling of GeneChip microarray expression
Background: Post-hybridization washing is an essential part of microarray experiments. Both the quality of the experimental washing protocol and adequate consideration of washing ...
Hans Binder, Knut Krohn, Conrad J. Burden
JCB
2000
103views more  JCB 2000»
13 years 7 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
BMCBI
2002
89views more  BMCBI 2002»
13 years 7 months ago
Sources of variability and effect of experimental approach on expression profiling data interpretation
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...