: Scattering of neutrons and x-rays from molecules in solution offers alternative approaches to the studying of a wide range of macromolecular structures in their solution state w...
Paritosh A. Kavathekar, Bruce A. Craig, Alan M. Fr...
This paper proposes the Protein Ensemble Method (PEM) to model equilibrium fluctuations in proteins where fragments of the protein polypeptide chain can move independently of one ...
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
We present a simple statistical model of molecular function evolution to predict protein function. The model description encodes general knowledge of how molecular function evolve...
Barbara E. Engelhardt, Michael I. Jordan, Steven E...