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BMCBI
2010
134views more  BMCBI 2010»
13 years 8 months ago
ScreenMill: A freely available software suite for growth measurement, analysis and visualization of high-throughput screen data
Background: Many high-throughput genomic experiments, such as Synthetic Genetic Array and yeast two-hybrid, use colony growth on solid media as a screen metric. These experiments ...
John C. Dittmar, Robert J. D. Reid, Rodney Rothste...
BMCBI
2008
154views more  BMCBI 2008»
13 years 8 months ago
Bayesian models and meta analysis for multiple tissue gene expression data following corticosteroid administration
Background: This paper addresses key biological problems and statistical issues in the analysis of large gene expression data sets that describe systemic temporal response cascade...
Yulan Liang, Arpad Kelemen
BMCBI
2007
168views more  BMCBI 2007»
13 years 8 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2010
124views more  BMCBI 2010»
13 years 8 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2010
208views more  BMCBI 2010»
13 years 8 months ago
Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models
Background: Genome sequencing projects have expanded the gap between the amount of known protein sequences and structures. The limitations of current high resolution structure det...
Kasper Stovgaard, Christian Andreetta, Jesper Ferk...