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    CSB
    2003
    IEEE
    130views Bioinformatics» more  CSB 2003»
    A Computational Approach to Reconstructing Gene Regulatory Networks
    14 years 22 days ago
    A Computational Approach to Reconstructing Gene Regulatory Networks
    Download  www.mrc-lmb.cam.ac.uk
    Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
    Xutao Deng, Hesham H. Ali
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    BMCBI
    2005
    94views more  BMCBI 2005»
    Visualization-based discovery and analysis of genomic aberrations in microarray data
    13 years 7 months ago
    Visualization-based discovery and analysis of genomic aberrations in microarray data
    Download  www.biomedcentral.com
    Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
    Chad L. Myers, Xing Chen, Olga G. Troyanskaya
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    BMCBI
    2008
    95views more  BMCBI 2008»
    Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
    13 years 7 months ago
    Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
    Download  www.biomedcentral.com
    Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
    Joseph W. Foley, Fumiaki Katagiri
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    BMCBI
    2002
    89views more  BMCBI 2002»
    Sources of variability and effect of experimental approach on expression profiling data interpretation
    13 years 7 months ago
    Sources of variability and effect of experimental approach on expression profiling data interpretation
    Download  www.biomedcentral.com
    Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
    Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
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    BMCBI
    2010
    132views more  BMCBI 2010»
    Parallel multiplicity and error discovery rate (EDR) in microarray experiments
    13 years 7 months ago
    Parallel multiplicity and error discovery rate (EDR) in microarray experiments
    Download  www.biomedcentral.com
    Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
    Wayne Wenzhong Xu, Clay J. Carter
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