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» Statistical analysis of domains in interacting protein pairs
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BMCBI
2007
102views more  BMCBI 2007»
13 years 9 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
BMCBI
2010
126views more  BMCBI 2010»
13 years 6 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
JIB
2010
107views more  JIB 2010»
13 years 3 months ago
Integration of -omics data and networks for biomedical research with VANTED
Increasingly, research focus in the fields of biology and medicine moves from the investigation of single phenomena to the analysis of complex cause and effect relationships. The ...
Christian Klukas, Falk Schreiber
BMCBI
2004
207views more  BMCBI 2004»
13 years 8 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
SMI
2005
IEEE
14 years 2 months ago
Volumetric Data Analysis using Morse-Smale Complexes
The 3D Morse-Smale complex is a fundamental topological construct that partitions the domain of a real-valued function into regions having uniform gradient flow behavior. In this...
Vijay Natarajan, Valerio Pascucci