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» Statistical analysis of domains in interacting protein pairs
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BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
CSB
2005
IEEE
118views Bioinformatics» more  CSB 2005»
14 years 1 months ago
A Protein Interaction Verification System Based on a Neural Network Algorithm
Large amounts of protein-protein interaction data have been identified using various genome-scale screening techniques. Although interaction data is a valuable resource, high-thro...
Min Su Lee, Seung-Soo Park, Min Kyung Kim
BIOCOMP
2006
13 years 9 months ago
Statistical Analysis of Long-Range Interactions in Proteins
We carry out a comprehensive study of long-range interactions on a large data set of non-homologous proteins. Our study reveals that the long-range interactions between amino acid...
Jinmiao Chen, Narendra S. Chaudhari
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein