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» Statistical analysis of domains in interacting protein pairs
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BMCBI
2010
125views more  BMCBI 2010»
13 years 9 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2008
95views more  BMCBI 2008»
13 years 9 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2010
86views more  BMCBI 2010»
13 years 9 months ago
Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
Background: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes...
Qian Liu, Jinyan Li
NAR
2011
191views Computer Vision» more  NAR 2011»
12 years 11 months ago
The protein common interface database (ProtCID) - a comprehensive database of interactions of homologous proteins in multiple cr
The protein common interface database (ProtCID) is a database that contains clusters of similar homodimeric and heterodimeric interfaces observed in multiple crystal forms (CFs). ...
Qifang Xu, Roland L. Dunbrack Jr.
NAR
2011
211views Computer Vision» more  NAR 2011»
12 years 11 months ago
DIMA 3.0: Domain Interaction Map
Domain Interaction MAp (DIMA, available at http:// webclu.bio.wzw.tum.de/dima) is a database of predicted and known interactions between protein domains. It integrates 5807 struct...
Qibin Luo, Philipp Pagel, Baiba Vilne, Dmitrij Fri...