Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
Efficiently detecting outliers or anomalies is an important problem in many areas of science, medicine and information technology. Applications range from data cleaning to clinica...
Matthew Eric Otey, Amol Ghoting, Srinivasan Partha...
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...