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BMCBI
2011
14 years 9 months ago
N-gram analysis of 970 microbial organisms reveals presence of biological language models
Background: It has been suggested previously that genome and proteome sequences show characteristics typical of natural-language texts such as “signature-style” word usage ind...
Hatice U. Osmanbeyoglu, Madhavi Ganapathiraju
BMCBI
2011
14 years 9 months ago
Simulated evolution applied to study the genetic code optimality using a model of codon reassignments
Background: As the canonical code is not universal, different theories about its origin and organization have appeared. The optimization or level of adaptation of the canonical ge...
Jose Santos, Ángel Monteagudo
BMCBI
2007
113views more  BMCBI 2007»
15 years 2 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
ISBI
2008
IEEE
16 years 3 months ago
Axonal bouton modeling, detection and distribution analysis for the study of neural circuit organization and plasticity
We propose a novel method for axonal bouton modeling and automated detection in populations of labeled neurons, as well as bouton distribution analysis for the study of neural cir...
Abhay Mavalankar, Amina Chebira, Christina A. Hall...
SIGMOD
2001
ACM
136views Database» more  SIGMOD 2001»
16 years 2 months ago
Selectivity Estimation using Probabilistic Models
Estimating the result size of complex queries that involve selection on multiple attributes and the join of several relations is a difficult but fundamental task in database query...
Lise Getoor, Benjamin Taskar, Daphne Koller