311 search results - page 30 / 63 » Statistical significance in biological sequence analysis |
BMCBI
2008
13 years 7 months ago
2008
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
BMCBI
2011
12 years 11 months ago
2011
Background: Gene set analysis (GSA) has become a successful tool to interpret gene expression profiles in terms of biological functions, molecular pathways, or genomic locations. ...
BMCBI
2011
12 years 11 months ago
2011
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
BMCBI
2007
13 years 7 months ago
2007
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
BMCBI
2007
13 years 7 months ago
2007
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...