311 search results - page 43 / 63 » Statistical significance in biological sequence analysis |
BMCBI
2008
13 years 7 months ago
2008
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
BMCBI
2007
13 years 7 months ago
2007
Background: Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) a...
ALMOB
2008
13 years 7 months ago
2008
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
BMCBI
2010
13 years 7 months ago
2010
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
BMCBI
2004
13 years 7 months ago
2004
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...