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» Statistical significance in biological sequence analysis
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EDM
2009
116views Data Mining» more  EDM 2009»
13 years 5 months ago
Determining the Significance of Item Order In Randomized Problem Sets
Researchers who make tutoring systems would like to know which sequences of educational content lead to the most effective learning by their students. The majority of data collecte...
Zachary A. Pardos, Neil T. Heffernan
TPDS
1998
112views more  TPDS 1998»
13 years 7 months ago
Parallel Computation in Biological Sequence Analysis
—A massive volume of biological sequence data is available in over 36 different databases worldwide, including the sequence data generated by the Human Genome project. These data...
Tieng K. Yap, Ophir Frieder, Robert L. Martino
BMCBI
2011
13 years 2 months ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
KDD
2006
ACM
156views Data Mining» more  KDD 2006»
14 years 8 months ago
Discovering significant OPSM subspace clusters in massive gene expression data
Order-preserving submatrixes (OPSMs) have been accepted as a biologically meaningful subspace cluster model, capturing the general tendency of gene expressions across a subset of ...
Byron J. Gao, Obi L. Griffith, Martin Ester, Steve...