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    BIODATAMINING
    2008
    163views more  BIODATAMINING 2008»
    Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
    13 years 8 months ago
    Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
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    Background: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in parti...
    Saravana K. Kumarasamy, Yunshi Wang, Vignesh Viswa...
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    BMCBI
    2010
    115views more  BMCBI 2010»
    CONAN: copy number variation analysis software for genome-wide association studies
    13 years 8 months ago
    CONAN: copy number variation analysis software for genome-wide association studies
    Download  www.biomedcentral.com
    Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
    Lukas Forer, Sebastian Schönherr, Hansi Wei&s...
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    BMCBI
    2010
    105views more  BMCBI 2010»
    Comparison of PGH2 binding site in prostaglandin synthases
    13 years 8 months ago
    Comparison of PGH2 binding site in prostaglandin synthases
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    Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
    Padmapriya Paragi-Vedanthi, Mukesh Doble
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    BMCBI
    2007
    120views more  BMCBI 2007»
    Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
    13 years 8 months ago
    Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
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    Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
    Xin Lu, David L. Perkins
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    BMCBI
    2007
    127views more  BMCBI 2007»
    The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
    13 years 8 months ago
    The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
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    Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
    Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
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