The problem of discovering novel motifs of binding sites is important to the understanding of gene regulatory networks. Motifs are generally represented by matrices (PWM or PSSM) o...
The rapid growth of the world wide web had made the problem of topic speci c resource discovery an important one in recent years. In this problem, it is desired to nd web pages wh...
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Nowadays, graph-based knowledge discovery algorithms do not consider numeric attributes (they are discarded in the preprocessing step, or they are treated as alphanumeric values w...
Oscar E. Romero, Jesus A. Gonzalez, Lawrence B. Ho...
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...