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    BMCBI
    2008
    202views more  BMCBI 2008»
    Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
    13 years 9 months ago
    Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
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    Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
    Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
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    BMCBI
    2007
    139views more  BMCBI 2007»
    Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
    13 years 9 months ago
    Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
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    Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
    Andrew S. Peek
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    BMCBI
    2007
    126views more  BMCBI 2007»
    High-throughput identification of interacting protein-protein binding sites
    13 years 9 months ago
    High-throughput identification of interacting protein-protein binding sites
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    Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
    Jo-Lan Chung, Wei Wang, Philip E. Bourne
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    BMCBI
    2008
    162views more  BMCBI 2008»
    Improved identification of conserved cassette exons using Bayesian networks
    13 years 9 months ago
    Improved identification of conserved cassette exons using Bayesian networks
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    Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
    Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
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    BMCBI
    2007
    128views more  BMCBI 2007»
    Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
    13 years 9 months ago
    Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
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    Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
    Oliviero Carugo
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