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» Structural Protein Interactions: From Months to Minutes
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IPPS
2009
IEEE
14 years 3 months ago
High-throughput protein structure determination using grid computing
Determining the X-ray crystallographic structures of proteins using the technique of molecular replacement (MR) can be a time and labor-intensive trial-and-error process, involvin...
Jason W. Schmidberger, Blair Bethwaite, Colin Enti...
BMCBI
2010
176views more  BMCBI 2010»
13 years 8 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
IJDMB
2007
114views more  IJDMB 2007»
13 years 8 months ago
A parallel edge-betweenness clustering tool for Protein-Protein Interaction networks
: The increasing availability of protein-protein interaction graphs (PPI) requires new efficient tools capable of extracting valuable biological knowledge from these networks. Amon...
Qiaofeng Yang, Stefano Lonardi
RECOMB
2008
Springer
14 years 9 months ago
Fast and Accurate Alignment of Multiple Protein Networks
Comparative analysis of protein networks has proven to be a powerful approach for elucidating network structure and predicting protein function and interaction. A fundamental chall...
Maxim Kalaev, Vineet Bafna, Roded Sharan
BMCBI
2007
124views more  BMCBI 2007»
13 years 8 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte