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BMCBI
2011
12 years 11 months ago
HomPPI: A Class of Sequence Homology Based Protein-Protein Interface Prediction Methods
Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Li C. Xue, Drena Dobbs, Vasant Honavar
BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
RECOMB
2008
Springer
14 years 8 months ago
Fast and Accurate Alignment of Multiple Protein Networks
Comparative analysis of protein networks has proven to be a powerful approach for elucidating network structure and predicting protein function and interaction. A fundamental chall...
Maxim Kalaev, Vineet Bafna, Roded Sharan
BMCBI
2002
108views more  BMCBI 2002»
13 years 7 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
ICANN
2009
Springer
13 years 11 months ago
Classification Based on Combination of Kernel Density Estimators
Abstract. A new classification algorithm based on combination of kernel density estimators is introduced. The method combines the estimators with different bandwidths what can be i...
Mateusz Kobos, Jacek Mandziuk