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BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
RECOMB
2003
Springer
14 years 8 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
NAR
2002
138views more  NAR 2002»
13 years 7 months ago
The Protein Information Resource: an integrated public resource of functional annotation of proteins
The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discov...
Cathy H. Wu, Hongzhan Huang, Leslie Arminski, Jorg...
NAR
2006
82views more  NAR 2006»
13 years 7 months ago
The RCSB PDB information portal for structural genomics
10 The RCSB Protein Data Bank (PDB) offers online tools, summary reports and target information related to the worldwide structural genomics initiatives from its portal at http://...
Andrei Kouranov, Lei Xie, Joanna de la Cruz, Li Ch...
ECCB
2008
IEEE
14 years 2 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial