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BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
164views more  BMCBI 2008»
13 years 7 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
RECOMB
2006
Springer
14 years 8 months ago
A Parameterized Algorithm for Protein Structure Alignment
This paper proposes a parameterized algorithm for aligning two protein structures, in the case where one protein structure is represented by a contact map graph and the other by a ...
Jinbo Xu, Feng Jiao, Bonnie Berger
CIBCB
2009
IEEE
13 years 9 months ago
DDPIn - Distance and density based protein indexing
Protein structure similarity and classification methods have many applications in protein function prediction and associated fields (e.g. drug discovery). In this paper, we propose...
David Hoksza