Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
This paper introduces a new architecture for automating the generalization of program structure and the recognition of common patterns in the area of malware analysis. By using ma...
We discuss how Case Based Reasoning (CBR) (see e.g. [1], [4]) philosophy of adaptation of some known situations to new similar ones can be realized in rough set framework [5] for c...
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...