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BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
ICCAD
2006
IEEE
152views Hardware» more  ICCAD 2006»
14 years 4 months ago
Performance-oriented statistical parameter reduction of parameterized systems via reduced rank regression
Process variations in modern VLSI technologies are growing in both magnitude and dimensionality. To assess performance variability, complex simulation and performance models param...
Zhuo Feng, Peng Li
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
ICSE
2008
IEEE-ACM
14 years 7 months ago
The economy of collective attention for situated knowledge collaboration in software development
Because the knowledge required for the construction of a complex software system is often widely distributed among its members, programmers routinely engage in collaboration with ...
Yunwen Ye, Kumiyo Nakakoji, Yasuhiro Yamamoto
BMCBI
2008
119views more  BMCBI 2008»
13 years 7 months ago
On deducing causality in metabolic networks
Background: Metabolic networks present a complex interconnected structure, whose understanding is in general a non-trivial task. Several formal approaches have been developed to s...
Chiara Bodei, Andrea Bracciali, Davide Chiarugi