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JOBIM
2000
14 years 14 days ago
InterDB, a Prediction-Oriented Protein Interaction Database for C. elegans
Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...
Nicolas Thierry-Mieg, Laurent Trilling
RECOMB
2006
Springer
14 years 9 months ago
Structural Alignment of Pseudoknotted RNA
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
Banu Dost, Buhm Han, Shaojie Zhang, Vineet Bafna
GECCO
2008
Springer
135views Optimization» more  GECCO 2008»
13 years 10 months ago
Context-dependent predictions and cognitive arm control with XCSF
While John Holland has always envisioned learning classifier systems (LCSs) as cognitive systems, most work on LCSs has focused on classification, datamining, and function appro...
Martin V. Butz, Oliver Herbort
BIBE
2006
IEEE
132views Bioinformatics» more  BIBE 2006»
14 years 3 months ago
Simplicity in RNA Secondary Structure Alignment: Towards biologically plausible alignments
Ribonucleic acid (RNA) molecules contain the genetic information that regulates the functions of organisms. Given two different molecules, a preserved function corresponds to a pr...
Rimon Mikhaiel, Guohui Lin, Eleni Stroulia
ICML
2009
IEEE
14 years 9 months ago
Boosting with structural sparsity
Despite popular belief, boosting algorithms and related coordinate descent methods are prone to overfitting. We derive modifications to AdaBoost and related gradient-based coordin...
John Duchi, Yoram Singer