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RECOMB
2004
Springer
14 years 10 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
JMLR
2012
12 years 16 days ago
Sample Complexity of Composite Likelihood
We present the first PAC bounds for learning parameters of Conditional Random Fields [12] with general structures over discrete and real-valued variables. Our bounds apply to com...
Joseph K. Bradley, Carlos Guestrin
BMCBI
2006
120views more  BMCBI 2006»
13 years 10 months ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu
JCB
2006
215views more  JCB 2006»
13 years 10 months ago
Protein Fold Recognition Using Segmentation Conditional Random Fields (SCRFs)
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...
WCC
2005
Springer
130views Cryptology» more  WCC 2005»
14 years 3 months ago
On the Design of Codes for DNA Computing
In this paper, we describe a broad class of problems arising in the context of designing codes for DNA computing. We primarily focus on design considerations pertaining to the phen...
Olgica Milenkovic, Navin Kashyap