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BMCBI
2010
83views more  BMCBI 2010»
13 years 9 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
BMCBI
2008
85views more  BMCBI 2008»
13 years 9 months ago
Wanted: unique names for unique atom positions. PDB-wide analysis of diastereotopic atom names of small molecules containing dip
Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...
Christopher A. Bottoms, Dong Xu
BMCBI
2006
115views more  BMCBI 2006»
13 years 9 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
FGCS
2006
74views more  FGCS 2006»
13 years 9 months ago
A performance model of non-deterministic particle transport on large-scale systems
In this work we present a predictive analytical model that encompasses the performance and scaling characteristics of a nondeterministic particle transport application, MCNP (Mont...
Mark M. Mathis, Darren J. Kerbyson, Adolfy Hoisie
SIAMSC
2008
131views more  SIAMSC 2008»
13 years 9 months ago
Gramian-Based Model Reduction for Data-Sparse Systems
Model order reduction (MOR) is common in simulation, control and optimization of complex dynamical systems arising in modeling of physical processes and in the spatial discretizati...
Ulrike Baur, Peter Benner
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