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BMCBI
2005
73views more  BMCBI 2005»
15 years 3 months ago
An analysis of extensible modelling for functional genomics data
Background: Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a mechanism for allowing e...
Andrew R. Jones, Norman W. Paton
138
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BMCBI
2005
104views more  BMCBI 2005»
15 years 3 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
150
Voted
BMCBI
2005
124views more  BMCBI 2005»
15 years 3 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
138
Voted
BMCBI
2005
246views more  BMCBI 2005»
15 years 3 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...
100
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TMI
2008
66views more  TMI 2008»
15 years 3 months ago
Feature Normalization via Expectation Maximization and Unsupervised Nonparametric Classification For M-FISH Chromosome Images
Multicolor fluorescence in situ hybridization (M-FISH) techniques provide color karyotyping that allows simultaneous analysis of numerical and structural abnormalities of whole hum...
Hyohoon Choi, Alan C. Bovik, Kenneth R. Castleman