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BMCBI
2008
135views more  BMCBI 2008»
13 years 10 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2008
154views more  BMCBI 2008»
13 years 10 months ago
Sequence based residue depth prediction using evolutionary information and predicted secondary structure
Background: Residue depth allows determining how deeply a given residue is buried, in contrast to the solvent accessibility that differentiates between buried and solvent-exposed ...
Hua Zhang, Tuo Zhang, Ke Chen 0003, Shiyi Shen, Ji...
BMCBI
2011
13 years 1 months ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson
BMCBI
2005
124views more  BMCBI 2005»
13 years 10 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
ISMIS
2005
Springer
14 years 3 months ago
Statistical Database Modeling for Privacy Preserving Database Generation
Abstract. Testing of database applications is of great importance. Although various studies have been conducted to investigate testing techniques for database design, relatively fe...
Xintao Wu, Yongge Wang, Yuliang Zheng