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BMCBI
2006
60views more  BMCBI 2006»
13 years 10 months ago
Use of a multi-way method to analyze the amino acid composition of a conserved group of orthologous proteins in prokaryotes
Background: Amino acids in proteins are not used equally. Some of the differences in the amino acid composition of proteins are between species (mainly due to nucleotide compositi...
Alberto Pasamontes, Santiago Garcia-Vallvé
BMCBI
2006
133views more  BMCBI 2006»
13 years 10 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
DCG
2006
163views more  DCG 2006»
13 years 10 months ago
Isometry-Invariant Valuations on Hyperbolic Space
Abstract. Hyperbolic area is characterized as the unique continuous isometry invariant simple valuation on convex polygons in H2 . We then show that continuous isometry invariant s...
Daniel A. Klain
BMCBI
2007
216views more  BMCBI 2007»
13 years 9 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BMCBI
2007
141views more  BMCBI 2007»
13 years 9 months ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...