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BMCBI
2010
134views more  BMCBI 2010»
13 years 9 months ago
Semi-automated screening of biomedical citations for systematic reviews
Background: Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and crit...
Byron C. Wallace, Thomas A. Trikalinos, Joseph Lau...
BMCBI
2008
137views more  BMCBI 2008»
13 years 9 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
BMCBI
2007
121views more  BMCBI 2007»
13 years 9 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
BMCBI
2007
207views more  BMCBI 2007»
13 years 9 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...
BMCBI
2008
170views more  BMCBI 2008»
13 years 9 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini