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UAI
2003
13 years 9 months ago
On the Convergence of Bound Optimization Algorithms
Many practitioners who use EM and related algorithms complain that they are sometimes slow. When does this happen, and what can be done about it? In this paper, we study the gener...
Ruslan Salakhutdinov, Sam T. Roweis, Zoubin Ghahra...
BMCBI
2010
125views more  BMCBI 2010»
13 years 7 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2008
228views more  BMCBI 2008»
13 years 7 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2008
72views more  BMCBI 2008»
13 years 7 months ago
HECTAR: A method to predict subcellular targeting in heterokonts
Background: The heterokonts are a particularly interesting group of eukaryotic organisms; they include many key species of planktonic and coastal algae and several important patho...
Bernhard Gschloessl, Yann Guermeur, J. Mark Cock