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BMCBI
2010
146views more  BMCBI 2010»
13 years 10 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
BMCBI
2007
175views more  BMCBI 2007»
13 years 10 months ago
Fast automated cell phenotype image classification
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
Nicholas A. Hamilton, Radosav S. Pantelic, Kelly H...
BMCBI
2006
172views more  BMCBI 2006»
13 years 9 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
PR
2008
141views more  PR 2008»
13 years 9 months ago
Robust and efficient multiclass SVM models for phrase pattern recognition
Phrase pattern recognition (phrase chunking) refers to automatic approaches for identifying predefined phrase structures in a stream of text. Support vector machines (SVMs)-based ...
Yu-Chieh Wu, Yue-Shi Lee, Jie-Chi Yang
BMCBI
2004
140views more  BMCBI 2004»
13 years 9 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard