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» Support Vector Training of Protein Alignment Models
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BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
FLAIRS
2008
13 years 9 months ago
Small Models of Large Machines
In this paper, we model large support vector machines (SVMs) by smaller networks in order to decrease the computational cost. The key idea is to generate additional training patte...
Pramod Lakshmi Narasimha, Sanjeev S. Malalur, Mich...
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
ICPR
2008
IEEE
14 years 1 months ago
Weighted solution path algorithm of support vector regression for abnormal data
In the solution path algorithm of support vector regression, the penalty for violation of the required error is considered equally for every training sample, which means every tra...
Wen-tao Mao, Long-lei Dong, Gang Zhang
BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...