Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
In this paper, we model large support vector machines (SVMs) by smaller networks in order to decrease the computational cost. The key idea is to generate additional training patte...
Pramod Lakshmi Narasimha, Sanjeev S. Malalur, Mich...
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
In the solution path algorithm of support vector regression, the penalty for violation of the required error is considered equally for every training sample, which means every tra...
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...