Protein phosphorylation is a crucial regulatory mechanism in various organisms. With recent improvements in mass spectrometry, phosphorylation site data are rapidly accumulating. D...
Jianjiong Gao, Ganesh Kumar Agrawal, Jay J. Thelen...
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
Protein fold recognition is the prediction of protein’s tertiary structure (Fold) given the protein’s sequence without relying on sequence similarity. Using machine learning t...
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...