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ASC
2010
13 years 9 months ago
Genotype representations in grammatical evolution
Grammatical evolution (GE) is a form of grammar-based genetic programming. A particular feature of GE is that it adopts a distinction between the genotype and phenotype similar to...
Jonatan Hugosson, Erik Hemberg, Anthony Brabazon, ...
BMCBI
2007
93views more  BMCBI 2007»
13 years 9 months ago
Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies
Background: Current efforts within the biomedical ontology community focus on achieving interoperability between various biomedical ontologies that cover a range of diverse domain...
Robert Hoehndorf, Frank Loebe, Janet Kelso, Heinri...
BMCBI
2010
108views more  BMCBI 2010»
13 years 9 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
BMCBI
2008
140views more  BMCBI 2008»
13 years 9 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003
BMCBI
2008
185views more  BMCBI 2008»
13 years 9 months ago
Mining clinical relationships from patient narratives
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
Angus Roberts, Robert J. Gaizauskas, Mark Hepple, ...