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BMCBI
2006
74views more  BMCBI 2006»
13 years 7 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane
BMCBI
2006
195views more  BMCBI 2006»
13 years 7 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona
BMCBI
2006
143views more  BMCBI 2006»
13 years 7 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
159views more  BMCBI 2006»
13 years 7 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2006
125views more  BMCBI 2006»
13 years 7 months ago
Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
Hiraku Morisawa, Mikako Hirota, Tosifusa Toda
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