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» Switch Detection in Genetic Regulatory Networks
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HYBRID
2007
Springer
14 years 1 months ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
CAV
2011
Springer
217views Hardware» more  CAV 2011»
12 years 10 months ago
From Cardiac Cells to Genetic Regulatory Networks
Abstract. A fundamental question in the treatment of cardiac disorders, such as tachycardia and fibrillation, is under what circumstances does such a disorder arise? To answer to ...
Radu Grosu, Grégory Batt, Flavio H. Fenton,...
JCB
2006
114views more  JCB 2006»
13 years 6 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
AUTOMATICA
2010
127views more  AUTOMATICA 2010»
13 years 5 months ago
Partitioning datasets based on equalities among parameters
When a phenomenon is described by a parametric model and multiple datasets are available, a key problem in statistics is to discover which datasets are characterized by the same p...
Riccardo Porreca, Giancarlo Ferrari-Trecate
HYBRID
2001
Springer
13 years 11 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic