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» Symbolic Modeling of Genetic Regulatory Networks
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TSP
2008
132views more  TSP 2008»
13 years 7 months ago
Robust Intervention in Probabilistic Boolean Networks
Probabilistic Boolean networks (PBNs) have been recently introduced as a paradigm for modeling genetic regulatory networks. One of the objectives of PBN modeling is to use the netw...
Ranadip Pal, Aniruddha Datta, Edward R. Dougherty
CEC
2008
IEEE
13 years 7 months ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
BMCBI
2007
197views more  BMCBI 2007»
13 years 7 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
ICCS
2005
Springer
14 years 1 months ago
Modelling Dynamics of Genetic Networks as a Multiscale Process
A key phenomenon in the dynamics of genetic networks is the cell cycle. In the study of this phenomenon, an important task is to understand how many processes, acting on different...
Xilin Wei, Roderick V. N. Melnik, Gabriel Moreno-H...
EVOW
2007
Springer
14 years 1 months ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler