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IDA
2009
Springer
13 years 5 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
Functional clustering of yeast proteins from the protein-protein interaction network
Background: The abundant data available for protein interaction networks have not yet been fully understood. New types of analyses are needed to reveal organizational principles o...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
Computationally efficient flux variability analysis
Background: Flux variability analysis is often used to determine robustness of metabolic models in various simulation conditions. However, its use has been somehow limited by the ...
Steinn Gudmundsson, Ines Thiele
CMSB
2010
Springer
13 years 2 months ago
Action-based analysis of discrete regulatory networks with short-term stimuli
To incorporate instant effects and different timescales within a single biological system, an extension of discrete regulatory networks with short-term stimuli is proposed. By mai...
Christian Krause, Carola Krause, Erik P. de Vink
RECOMB
2012
Springer
11 years 10 months ago
Reconstructing Boolean Models of Signaling
Abstract. Since the first emergence of protein-protein interaction networks, more than a decade ago, they have been viewed as static scaffolds of the signaling-regulatory events ...
Roded Sharan, Richard M. Karp