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» Symbolic Systems Biology: Hybrid Modeling and Analysis of Bi...
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BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
svdPPCS: an effective singular value decomposition-based method for conserved and divergent co-expression gene module identifica
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
Wensheng Zhang, Andrea Edwards, Wei Fan, Dongxiao ...
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
RECOMB
2007
Springer
14 years 1 months ago
Network Legos: Building Blocks of Cellular Wiring Diagrams
Publicly-available data sets provide detailed and large-scale information on multiple types of molecular interaction networks in a number of model organisms. These multi-modal univ...
T. M. Murali, Corban G. Rivera
GECCO
2010
Springer
173views Optimization» more  GECCO 2010»
13 years 11 months ago
The baldwin effect in developing neural networks
The Baldwin Effect is a very plausible, but unproven, biological theory concerning the power of learning to accelerate evolution. Simple computational models in the 1980’s gave...
Keith L. Downing
BMCBI
2006
141views more  BMCBI 2006»
13 years 7 months ago
Visual setup of logical models of signaling and regulatory networks with ProMoT
Background: The analysis of biochemical networks using a logical (Boolean) description is an important approach in Systems Biology. Recently, new methods have been proposed to ana...
Julio Saez-Rodriguez, Sebastian Mirschel, Rebecca ...