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BMCBI
2007
157views more  BMCBI 2007»
13 years 8 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
BMCBI
2007
169views more  BMCBI 2007»
13 years 8 months ago
Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana
Background: The central role of transcription factors (TFs) in higher eukaryotes has led to much interest in deciphering transcriptional regulatory interactions. Even in the best ...
Henning Redestig, Daniel Weicht, Joachim Selbig, M...
BMCBI
2008
259views more  BMCBI 2008»
13 years 8 months ago
DISCLOSE : DISsection of CLusters Obtained by SEries of transcriptome data using functional annotations and putative transcripti
Background: A typical step in the analysis of gene expression data is the determination of clusters of genes that exhibit similar expression patterns. Researchers are confronted w...
Evert-Jan Blom, Sacha A. F. T. van Hijum, Klaas J....
BMCBI
2007
154views more  BMCBI 2007»
13 years 8 months ago
h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
Background: An ever increasing number of techniques are being used to find genes with similar profiles from microarray studies. Visualization of gene expression profiles can aid t...
Yvonne E. Pittelkow, Susan R. Wilson
BMCBI
2005
97views more  BMCBI 2005»
13 years 8 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles