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BMCBI
2010
172views more  BMCBI 2010»
13 years 11 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BMCBI
2010
147views more  BMCBI 2010»
13 years 11 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BMCBI
2010
141views more  BMCBI 2010»
13 years 11 months ago
CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies
Background: Immunoglobulin (IG or antibody) and the T-cell receptor (TR) are pivotal proteins in the immune system of higher organisms. In cancer immunotherapy, the immune respons...
Yoji Nakamura, Tomoyoshi Komiyama, Motoki Furue, T...
BMCBI
2008
128views more  BMCBI 2008»
13 years 11 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...
BMCBI
2008
83views more  BMCBI 2008»
13 years 11 months ago
Terminologies for text-mining; an experiment in the lipoprotein metabolism domain
Background: The engineering of ontologies, especially with a view to a text-mining use, is still a new research field. There does not yet exist a well-defined theory and technolog...
Dimitra Alexopoulou, Thomas Wächter, Laura Pi...
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