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ICGA
1997
122views Optimization» more  ICGA 1997»
13 years 11 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
GECCO
2006
Springer
143views Optimization» more  GECCO 2006»
14 years 1 months ago
Hybrid search for cardinality constrained portfolio optimization
In this paper, we describe how a genetic algorithm approach added to a simulated annealing (SA) process offers a better alternative to find the mean variance frontier in the portf...
Miguel A. Gomez, Carmen X. Flores, Maria A. Osorio
GECCO
2008
Springer
108views Optimization» more  GECCO 2008»
13 years 11 months ago
Search space reduction technique for constrained optimization with tiny feasible space
The hurdles in solving Constrained Optimization Problems (COP) arise from the challenge of searching a huge variable space in order to locate feasible points with acceptable solut...
Abu S. S. M. Barkat Ullah, Ruhul A. Sarker, David ...
SIGMOD
2010
ACM
196views Database» more  SIGMOD 2010»
14 years 1 months ago
Connected substructure similarity search
Substructure similarity search is to retrieve graphs that approximately contain a given query graph. It has many applications, e.g., detecting similar functions among chemical com...
Haichuan Shang, Xuemin Lin, Ying Zhang, Jeffrey Xu...
ISPD
1998
ACM
89views Hardware» more  ISPD 1998»
14 years 2 months ago
Filling and slotting: analysis and algorithms
In very deep-submicron VLSI, certain manufacturing steps – notably optical exposure, resist development and etch, chemical vapor deposition and chemical-mechanical polishing (CM...
Andrew B. Kahng, Gabriel Robins, Anish Singh, Huij...