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» Target SNP selection in complex disease association studies
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WABI
2007
Springer
109views Bioinformatics» more  WABI 2007»
14 years 5 months ago
Two Birds, One Stone: Selecting Functionally Informative Tag SNPs for Disease Association Studies
Selecting an informative subset of SNPs, generally referred to as tag SNPs, to genotype and analyze is considered to be an essential step toward effective disease association studi...
Phil Hyoun Lee, Hagit Shatkay
BMCBI
2006
190views more  BMCBI 2006»
13 years 11 months ago
SNPs3D: Candidate gene and SNP selection for association studies
Background: The relationship between disease susceptibility and genetic variation is complex, and many different types of data are relevant. We describe a web resource and databas...
Peng Yue, Eugene Melamud, John Moult
BMCBI
2010
146views more  BMCBI 2010»
13 years 11 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
CIBCB
2008
IEEE
14 years 5 months ago
Very large scale ReliefF for genome-wide association analysis
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
Margaret J. Eppstein, Paul Haake